Synergistic pH effect for reversible shuttling aptamer-based biosensors between graphene oxide and target molecules
| dc.contributor.author | Huang, Po-Jung Jimmy | |
| dc.contributor.author | Kempaiah, Ravindra | |
| dc.contributor.author | Liu, Juewen | |
| dc.date.accessioned | 2017-03-20T17:02:38Z | |
| dc.date.available | 2017-03-20T17:02:38Z | |
| dc.date.issued | 2011-06-07 | |
| dc.description.abstract | DNA aptamers are known to desorb from graphene oxide (GO) surface in the presence of target molecules. We demonstrate herein that the binding equilibrium can be shifted by simply tuning the solution pH. At lower pH, the aptamer/GO binding is enhanced while aptamer/target binding is weakened, making this system a regenerable biosensor without covalent conjugation. | en |
| dc.description.sponsorship | University of Waterloo || Natural Sciences and Engineering Research Council || | en |
| dc.identifier.uri | http://dx.doi.org/10.1039/C1JM11702E | |
| dc.identifier.uri | http://hdl.handle.net/10012/11541 | |
| dc.language.iso | en | en |
| dc.publisher | Royal Society of Chemistry | en |
| dc.subject | pH | en |
| dc.subject | biosensors | en |
| dc.subject | graphene oxide | en |
| dc.subject | DNA | en |
| dc.title | Synergistic pH effect for reversible shuttling aptamer-based biosensors between graphene oxide and target molecules | en |
| dc.type | Article | en |
| dcterms.bibliographicCitation | Huang, P. J. J., Kempaiah, R., & Liu, J. (2011). Synergistic pH effect for reversible shuttling aptamer-based biosensors between graphene oxide and target molecules. Journal of Materials Chemistry, 21(25), 8991-8993. | en |
| uws.contributor.affiliation1 | Faculty of Science | en |
| uws.contributor.affiliation2 | Chemistry | en |
| uws.contributor.affiliation2 | Waterloo Institute for Nanotechnology (WIN) | en |
| uws.peerReviewStatus | Reviewed | en |
| uws.scholarLevel | Faculty | en |
| uws.typeOfResource | Text | en |