Biomimetic sensing based on chemically induced assembly of a signaling DNA aptamer on a fluid bilayer membrane
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Date
2012-04-18
Authors
Dave, Neeshma
Liu, Juewen
Journal Title
Journal ISSN
Volume Title
Publisher
Royal Society of Chemistry
Abstract
The adenosine aptamer was split into two halves and linked to a fluid liposome surface; addition of adenosine resulted in aptamer assembly, which did not occur if the split aptamer was attached to silica nanoparticles, demonstrating the feasibility of using aptamer probes to study diffusion within lipid membranes.
Description
Keywords
DNA, lipid bilayer, FRET, adenosine