A platinum shell for ultraslow ligand exchange: unmodified DNA adsorbing more stably on platinum than thiol and dithiol on gold
| dc.contributor.author | Zhou, Wenhu | |
| dc.contributor.author | Ding, Jinsong | |
| dc.contributor.author | Liu, Juewen | |
| dc.date.accessioned | 2017-02-23T20:24:24Z | |
| dc.date.available | 2017-02-23T20:24:24Z | |
| dc.date.issued | 2015-08-04 | |
| dc.description.abstract | Due to the ultraslow ligand exchange rate on Pt, non-thiolated DNA is adsorbed on platinum nanoparticles (PtNPs) more stably than thiolated and even dithiolated DNA on AuNPs. Adsorption kinetics, capacity and stability are systematically compared as a function of DNA sequence. The Pt conjugates can tolerate extreme pH, salt, and thiol molecules. Taking advantage of the optical properties of AuNPs and the extreme stability of DNA on PtNPs, DNA-functionalized Au@Pt NPs are prepared using a cost-effective and more stable bioconjugation method. The DNA-directed assembly of non-thiolated DNA conjugates is also demonstrated. | en |
| dc.description.sponsorship | University of Waterloo || Natural Sciences and Engineering Research Council || Foundation for Shenghua Scholar of Central South University || National Natural Science Foundation of China || Grant No. 21301195 China Scholarship Council || CSC, Grant No. 201406370116 | en |
| dc.identifier.uri | http://dx.doi.org/10.1039/C5CC04340A | |
| dc.identifier.uri | http://hdl.handle.net/10012/11343 | |
| dc.language.iso | en | en |
| dc.publisher | Royal Society of Chemistry | en |
| dc.subject | DNA | en |
| dc.subject | Ligand Exchange | en |
| dc.subject | gold | en |
| dc.subject | platinum | en |
| dc.subject | adsorption | en |
| dc.title | A platinum shell for ultraslow ligand exchange: unmodified DNA adsorbing more stably on platinum than thiol and dithiol on gold | en |
| dc.type | Article | en |
| dcterms.bibliographicCitation | Zhou, W., Ding, J., & Liu, J. (2015). A platinum shell for ultraslow ligand exchange: unmodified DNA adsorbing more stably on platinum than thiol and dithiol on gold. Chem. Commun., 51(60), 12084–12087. https://doi.org/10.1039/C5CC04340A | en |
| uws.contributor.affiliation1 | Faculty of Science | en |
| uws.contributor.affiliation2 | Chemistry | en |
| uws.contributor.affiliation2 | Waterloo Institute for Nanotechnology (WIN) | en |
| uws.peerReviewStatus | Reviewed | en |
| uws.scholarLevel | Faculty | en |
| uws.typeOfResource | Text | en |